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Ras and p53: An unsuspected liaison
The precise mechanism by which Ras proteins mediate mitogenic signaling remains obscure. We have identified the p53/p21Cip1 axis as an essential component of the Ras mitogenic pathway. Moreover, cells carrying an inactive p53/p21Cip1/Rb pathway sustain cell proliferation by inducing retroactivation...
Tallennettuna:
| Julkaisussa: | Mol Cell Oncol |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Taylor & Francis
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905429/ https://ncbi.nlm.nih.gov/pubmed/27308624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2014.996001 |
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