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Ras and p53: An unsuspected liaison

The precise mechanism by which Ras proteins mediate mitogenic signaling remains obscure. We have identified the p53/p21Cip1 axis as an essential component of the Ras mitogenic pathway. Moreover, cells carrying an inactive p53/p21Cip1/Rb pathway sustain cell proliferation by inducing retroactivation...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Mol Cell Oncol
Päätekijät: Drosten, Matthias, Barbacid, Mariano
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905429/
https://ncbi.nlm.nih.gov/pubmed/27308624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2014.996001
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