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Protein Folding—How and Why: By Hydrogen Exchange, Fragment Separation, and Mass Spectrometry
Advanced hydrogen exchange (HX) methodology can now determine the structure of protein folding intermediates and their progression in folding pathways. Key developments over time include the HX pulse labeling method with nuclear magnetic resonance analysis, development of the fragment separation met...
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| Veröffentlicht in: | Annu Rev Biophys |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5588872/ https://ncbi.nlm.nih.gov/pubmed/27145881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biophys-062215-011121 |
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