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Recombination initiation maps of individual human genomes
DNA double-strand breaks (DSBs) are introduced in meiosis to initiate recombination and generate crossovers, the reciprocal exchanges of genetic material between parental chromosomes. Here we present high-resolution maps of meiotic DSBs in individual human genomes. Comparing DSB maps between individ...
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| Pubblicato in: | Science |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5588152/ https://ncbi.nlm.nih.gov/pubmed/25395542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1256442 |
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