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Sensitive mapping of recombination hotspots using sequencing-based detection of ssDNA
Meiotic DNA double-stranded breaks (DSBs) initiate genetic recombination in discrete areas of the genome called recombination hotspots. DSBs can be directly mapped using chromatin immunoprecipitation followed by sequencing (ChIP-seq). Nevertheless, the genome-wide mapping of recombination hotspots i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337440/ https://ncbi.nlm.nih.gov/pubmed/22367190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.130583.111 |
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