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The evolutionary turnover of recombination hot spots contributes to speciation in mice
Meiotic recombination is required for the segregation of homologous chromosomes and is essential for fertility. In most mammals, the DNA double-strand breaks (DSBs) that initiate meiotic recombination are directed to a subset of genomic loci (hot spots) by sequence-specific binding of the PRDM9 prot...
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| Gepubliceerd in: | Genes Dev |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cold Spring Harbor Laboratory Press
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4743057/ https://ncbi.nlm.nih.gov/pubmed/26833728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.270009.115 |
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