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Extensive sex differences at the initiation of genetic recombination

Meiotic recombination differs between males and females; however, when and how these differences are established is unknown. Here we identify extensive sex differences at recombination initiation by mapping hotspots of meiotic DNA double-strand breaks in male and female mice. Contrary to past findin...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Brick, Kevin, Thibault-Sennett, Sarah, Smagulova, Fatima, Lam, Kwan-Wood G., Pu, Yongmei, Pratto, Florencia, Camerini-Otero, R. Daniel, Petukhova, Galina V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364566/
https://ncbi.nlm.nih.gov/pubmed/30185906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0492-5
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