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Genetic recombination is directed away from functional genomic elements in mice

Genetic recombination occurs during meiosis, the key developmental program of gametogenesis. Recombination in mammals has been recently linked to the activity of a histone H3 methyl-transferase, PRDM9(1–6), the product of the only known speciation gene in mammals(7). PRDM9 is thought to determine th...

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Autors principals: Brick, Kevin, Smagulova, Fatima, Khil, Pavel, Camerini-Otero, R. Daniel, Petukhova, Galina V.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367396/
https://ncbi.nlm.nih.gov/pubmed/22660327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11089
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