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Genetic recombination is directed away from functional genomic elements in mice

Genetic recombination occurs during meiosis, the key developmental program of gametogenesis. Recombination in mammals has been recently linked to the activity of a histone H3 methyl-transferase, PRDM9(1–6), the product of the only known speciation gene in mammals(7). PRDM9 is thought to determine th...

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Detalhes bibliográficos
Main Authors: Brick, Kevin, Smagulova, Fatima, Khil, Pavel, Camerini-Otero, R. Daniel, Petukhova, Galina V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367396/
https://ncbi.nlm.nih.gov/pubmed/22660327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11089
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