Sensitive mapping of recombination hotspots using sequencing-based detection of ssDNA

Meiotic DNA double-stranded breaks (DSBs) initiate genetic recombination in discrete areas of the genome called recombination hotspots. DSBs can be directly mapped using chromatin immunoprecipitation followed by sequencing (ChIP-seq). Nevertheless, the genome-wide mapping of recombination hotspots i...

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Detaylı Bibliyografya
Asıl Yazarlar: Khil, Pavel P., Smagulova, Fatima, Brick, Kevin M., Camerini-Otero, R. Daniel, Petukhova, Galina V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2012
Konular:
Method
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337440/
https://ncbi.nlm.nih.gov/pubmed/22367190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.130583.111
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