Lack of chemopreventive efficacy of metformin in rodent models of urinary bladder, head and neck, and colon/intestine cancer

Metformin is a biguanide employed in treating type II diabetes. Its potential efficacy for treating cancer has been demonstrated epidemiologically (lower cancer incidence in metformin users compared with users of sulfonylureas or insulin) and mechanistically, primarily in cell culture. Metformin dec...

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Foilsithe in:Oncol Lett
Main Authors: Thompson, Matthew D., Lubet, Ronald A., Mccormick, David L., Clapper, Margie L., Bode, Ann M., Juliana, M. Margaret, Moeinpour, Fariba, Grubbs, Clinton J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: D.A. Spandidos 2017
Ábhair:
Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587978/
https://ncbi.nlm.nih.gov/pubmed/28927103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6632
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