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Lack of chemopreventive efficacy of metformin in rodent models of urinary bladder, head and neck, and colon/intestine cancer

Metformin is a biguanide employed in treating type II diabetes. Its potential efficacy for treating cancer has been demonstrated epidemiologically (lower cancer incidence in metformin users compared with users of sulfonylureas or insulin) and mechanistically, primarily in cell culture. Metformin dec...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Thompson, Matthew D., Lubet, Ronald A., Mccormick, David L., Clapper, Margie L., Bode, Ann M., Juliana, M. Margaret, Moeinpour, Fariba, Grubbs, Clinton J.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587978/
https://ncbi.nlm.nih.gov/pubmed/28927103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6632
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