Lack of chemopreventive efficacy of metformin in rodent models of urinary bladder, head and neck, and colon/intestine cancer

Metformin is a biguanide employed in treating type II diabetes. Its potential efficacy for treating cancer has been demonstrated epidemiologically (lower cancer incidence in metformin users compared with users of sulfonylureas or insulin) and mechanistically, primarily in cell culture. Metformin dec...

Full description

Saved in:
Bibliographic Details
Published in:Oncol Lett
Main Authors: Thompson, Matthew D., Lubet, Ronald A., Mccormick, David L., Clapper, Margie L., Bode, Ann M., Juliana, M. Margaret, Moeinpour, Fariba, Grubbs, Clinton J.
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2017
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587978/
https://ncbi.nlm.nih.gov/pubmed/28927103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6632
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items