Selective tumor cell death induced by irradiated riboflavin through recognizing DNA G–T mismatch

Riboflavin (vitamin B2) has been thought to be a promising antitumoral agent in photodynamic therapy, though the further application of the method was limited by the unclear molecular mechanism. Our work reveals that riboflavin was able to recognize G–T mismatch specifically and induce single-strand...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Yuan, Yi, Zhao, Yongyun, Chen, Lianqi, Wu, Jiasi, Chen, Gangyi, Li, Sheng, Zou, Jiawei, Chen, Rong, Wang, Jian, Jiang, Fan, Tang, Zhuo
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Chemical Biology and Nucleic Acid Chemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587794/
https://ncbi.nlm.nih.gov/pubmed/28911109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx602
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