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Sequence-specific RNA Photocleavage by Single-stranded DNA in Presence of Riboflavin

Constant efforts have been made to develop new method to realize sequence-specific RNA degradation, which could cause inhibition of the expression of targeted gene. Herein, by using an unmodified short DNA oligonucleotide for sequence recognition and endogenic small molecue, vitamin B2 (riboflavin)...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhao, Yongyun, Chen, Gangyi, Yuan, Yi, Li, Na, Dong, Juan, Huang, Xin, Cui, Xin, Tang, Zhuo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602204/
https://ncbi.nlm.nih.gov/pubmed/26461456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15039
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