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Sequence-specific RNA Photocleavage by Single-stranded DNA in Presence of Riboflavin

Constant efforts have been made to develop new method to realize sequence-specific RNA degradation, which could cause inhibition of the expression of targeted gene. Herein, by using an unmodified short DNA oligonucleotide for sequence recognition and endogenic small molecue, vitamin B2 (riboflavin)...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Zhao, Yongyun, Chen, Gangyi, Yuan, Yi, Li, Na, Dong, Juan, Huang, Xin, Cui, Xin, Tang, Zhuo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602204/
https://ncbi.nlm.nih.gov/pubmed/26461456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15039
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