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Mismatches and Bubbles in DNA

Single mismatches in the DNA double helix form nucleation sites for bubbles. Although the overall melting temperature of the duplex is affected to different degrees depending on the probe length, the statistical weights of the bubble states around the defect are always strongly affected. Here we sho...

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Bibliographic Details
Main Authors: Zeng, Yan, Zocchi, Giovanni
Format: Artigo
Language:Inglês
Published: Biophysical Society 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1471854/
https://ncbi.nlm.nih.gov/pubmed/16565068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.069591
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