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Hg(II) binds to C–T mismatches with high affinity
Binding reactions of Hg(II) and Ag(I) to pyrimidine-pyrimidine mismatches in duplex DNA were characterized using fluorescent nucleobase analogs, thermal denaturation and (1)H NMR. Unlike Ag(I), Hg(II) exhibited stoichiometric, site-specific binding of C–T mismatches. The on- and off-rates of Hg(II)...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6061796/ https://ncbi.nlm.nih.gov/pubmed/29901748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky499 |
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