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Cytosolic delivery of siRNA by ultra-high affinity dsRNA binding proteins
Protein-based methods of siRNA delivery are capable of uniquely specific targeting, but are limited by technical challenges such as low potency or poor biophysical properties. Here, we engineered a series of ultra-high affinity siRNA binders based on the viral protein p19 and developed them into siR...
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| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5570165/ https://ncbi.nlm.nih.gov/pubmed/28641400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx546 |
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