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OneBac 2.0: Sf9 Cell Lines for Production of AAV1, AAV2, and AAV8 Vectors with Minimal Encapsidation of Foreign DNA

Recombinant adeno-associated viral (rAAV) vectors for human gene therapy require efficient and economical production methods to keep pace with the rapidly increasing clinical demand. In addition, the manufacturing process must ensure high vector quality and biological safety. The OneBac system offer...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Hum Gene Ther Methods
Egile Nagusiak: Mietzsch, Mario, Hering, Henrik, Hammer, Eva-Maria, Agbandje-McKenna, Mavis, Zolotukhin, Sergei, Heilbronn, Regine
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Mary Ann Liebert, Inc. 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586161/
https://ncbi.nlm.nih.gov/pubmed/28125901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2016.164
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