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OneBac: Platform for Scalable and High-Titer Production of Adeno-Associated Virus Serotype 1–12 Vectors for Gene Therapy

Scalable and genetically stable recombinant adeno-associated virus (rAAV) production systems combined with facile adaptability for an extended repertoire of AAV serotypes are required to keep pace with the rapidly increasing clinical demand. For scalable high-titer production of the full range of rA...

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Autores principales: Mietzsch, Mario, Grasse, Sabrina, Zurawski, Catherine, Weger, Stefan, Bennett, Antonette, Agbandje-McKenna, Mavis, Muzyczka, Nicholas, Zolotukhin, Sergei, Heilbronn, Regine
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955967/
https://ncbi.nlm.nih.gov/pubmed/24299301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2013.184
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