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OneBac 2.0: Sf9 Cell Lines for Production of AAV1, AAV2, and AAV8 Vectors with Minimal Encapsidation of Foreign DNA

Recombinant adeno-associated viral (rAAV) vectors for human gene therapy require efficient and economical production methods to keep pace with the rapidly increasing clinical demand. In addition, the manufacturing process must ensure high vector quality and biological safety. The OneBac system offer...

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Bibliografiske detaljer
Udgivet i:Hum Gene Ther Methods
Main Authors: Mietzsch, Mario, Hering, Henrik, Hammer, Eva-Maria, Agbandje-McKenna, Mavis, Zolotukhin, Sergei, Heilbronn, Regine
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586161/
https://ncbi.nlm.nih.gov/pubmed/28125901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2016.164
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