Adeno-associated Virus (AAV) Capsid Chimeras with Enhanced Infectivity Reveal a Core Element in the AAV Genome Critical for both Cell Transduction and Capsid Assembly

Adeno-associated viruses (AAVs) have attracted significant attention in the field of gene and cell therapy due to their use in highly effective delivery of therapeutic genes into human cells. The ability to generate recombinant AAV (rAAV) vectors comprising unique or substituted protein sequences ha...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Viney, Lydia, Bürckstümmer, Tilmann, Eddington, Courtnee, Mietzsch, Mario, Choudhry, Modassir, Henley, Tom, Agbandje-McKenna, Mavis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Gene Delivery
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092683/
https://ncbi.nlm.nih.gov/pubmed/33441336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02023-20
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados