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Identifying DNase I hypersensitive sites as driver distal regulatory elements in breast cancer
Efforts to identify driver mutations in cancer have largely focused on genes, whereas non-coding sequences remain relatively unexplored. Here we develop a statistical method based on characteristics known to influence local mutation rate and a series of enrichment filters in order to identify distal...
में बचाया:
| में प्रकाशित: | Nat Commun |
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| मुख्य लेखकों: | , , , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group UK
2017
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5585396/ https://ncbi.nlm.nih.gov/pubmed/28874753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00100-x |
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