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Identification of cancer driver genes based on nucleotide context
Cancer genomes contain large numbers of somatic mutations, but few of these mutations drive tumor development. Current approaches identify driver genes based on mutational recurrence, or they approximate the functional consequences of nonsynonymous mutations using bioinformatic scores. While passeng...
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| Publicado no: | Nat Genet |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7031046/ https://ncbi.nlm.nih.gov/pubmed/32015527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0572-y |
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