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The mystery of missing heritability: Genetic interactions create phantom heritability

Human genetics has been haunted by the mystery of “missing heritability” of common traits. Although studies have discovered >1,200 variants associated with common diseases and traits, these variants typically appear to explain only a minority of the heritability. The proportion of heritability ex...

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Detalhes bibliográficos
Main Authors: Zuk, Or, Hechter, Eliana, Sunyaev, Shamil R., Lander, Eric S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268279/
https://ncbi.nlm.nih.gov/pubmed/22223662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119675109
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