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Measuring missing heritability: Inferring the contribution of common variants

Genome-wide association studies (GWASs), also called common variant association studies (CVASs), have uncovered thousands of genetic variants associated with hundreds of diseases. However, the variants that reach statistical significance typically explain only a small fraction of the heritability. O...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Golan, David, Lander, Eric S., Rosset, Saharon
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267399/
https://ncbi.nlm.nih.gov/pubmed/25422463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419064111
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