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Measuring missing heritability: Inferring the contribution of common variants

Genome-wide association studies (GWASs), also called common variant association studies (CVASs), have uncovered thousands of genetic variants associated with hundreds of diseases. However, the variants that reach statistical significance typically explain only a small fraction of the heritability. O...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Golan, David, Lander, Eric S., Rosset, Saharon
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267399/
https://ncbi.nlm.nih.gov/pubmed/25422463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419064111
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