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Limitations of GCTA as a solution to the missing heritability problem

Genome-wide association studies (GWASs) seek to understand the relationship between complex phenotype(s) (e.g., height) and up to millions of single-nucleotide polymorphisms (SNPs). Early analyses of GWASs are commonly believed to have “missed” much of the additive genetic variance estimated from co...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Krishna Kumar, Siddharth, Feldman, Marcus W., Rehkopf, David H., Tuljapurkar, Shripad
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711841/
https://ncbi.nlm.nih.gov/pubmed/26699465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520109113
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