DNase I–hypersensitive exons colocalize with promoters and distal regulatory elements

The precise splicing of genes confers an enormous transcriptional complexity to the human genome. The majority of gene splicing occurs cotranscriptionally, permitting epigenetic modifications to affect splicing outcomes. Here we show that select exonic regions are demarcated within the three-dimensi...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Mercer, Tim R, Edwards, Stacey L, Clark, Michael B, Neph, Shane J, Wang, Hao, Stergachis, Andrew B, John, Sam, Sandstrom, Richard, Li, Guoliang, Sandhu, Kuljeet S, Ruan, Yijun, Nielsen, Lars K, Mattick, John S, Stamatoyannopoulos, John A
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405174/
https://ncbi.nlm.nih.gov/pubmed/23793028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2677
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