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Gammaretroviral Vector Integration Occurs Overwhelmingly Within and Near DNase Hypersensitive Sites
Concerns surrounding the oncogenic potential of recombinant gammaretroviral vectors has spurred a great deal of interest in vector integration site (VIS) preferences. Although gammaretroviral vectors exhibit a modest preference for integration near transcription start sites (TSS) of active genes, su...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Mary Ann Liebert, Inc.
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3277727/ https://ncbi.nlm.nih.gov/pubmed/21981728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2010.177 |
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