A semi-invariant V(α)10(+) T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen–recognition properties

Type I natural killer T cells (NKT cells) are characterized by an invariant variable region 14–joining region 18 (V(α)14-V(α)18) T cell antigen receptor (TCR) α-chain and recognition of the glycolipid α-galactosylceramide (α-GalCer) restricted to the antigen-presenting molecule CD1d. Here we describ...

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Pubblicato in:Nat Immunol
Autori principali: Uldrich, Adam P, Patel, Onisha, Cameron, Garth, Pellicci, Daniel G, Day, E Bridie, Sullivan, Lucy C, Kyparissoudis, Konstantinos, Kjer-Nielsen, Lars, Vivian, Julian P, Cao, Benjamin, Brooks, Andrew G, Williams, Spencer J, Illarionov, Petr, Besra, Gurdyal S, Turner, Stephen J, Porcelli, Steven A, McCluskey, James, Smyth, Mark J, Rossjohn, Jamie, Godfrey, Dale I
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584938/
https://ncbi.nlm.nih.gov/pubmed/21666690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2051
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