Vβ2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen

Natural killer T cell antigen receptors (NKT TCRs) recognize lipid-based antigens (Ags) presented by CD1d. Although the TCR α-chain is invariant, NKT TCR Vβ exhibits greater diversity, with one (Vβ11) and three (Vβ8, Vβ7, and Vβ2) Vβ chains in humans and mice, respectively. With the exception of the...

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Hauptverfasser: Patel, Onisha, Pellicci, Daniel G., Uldrich, Adam P., Sullivan, Lucy C., Bhati, Mugdha, McKnight, Melissa, Richardson, Stewart K., Howell, Amy R., Mallevaey, Thierry, Zhang, Jingjing, Bedel, Romain, Besra, Gurdyal S., Brooks, Andrew G., Kjer-Nielsen, Lars, McCluskey, James, Porcelli, Steven A., Gapin, Laurent, Rossjohn, Jamie, Godfrey, Dale I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223435/
https://ncbi.nlm.nih.gov/pubmed/22065767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109066108
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