Human and Mouse Type I Natural Killer T Cell Antigen Receptors Exhibit Different Fine Specificities for CD1d-Antigen Complex

Human and mouse type I natural killer T (NKT) cells respond to a variety of CD1d-restricted glycolipid antigens (Ags), with their NKT cell antigen receptors (NKT TCRs) exhibiting reciprocal cross-species reactivity that is underpinned by a conserved NKT TCR-CD1d-Ag docking mode. Within this common d...

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Bibliografiset tiedot
Päätekijät: Wun, Kwok S., Ross, Fiona, Patel, Onisha, Besra, Gurdyal S., Porcelli, Steven A., Richardson, Stewart K., Keshipeddy, Santosh, Howell, Amy R., Godfrey, Dale I., Rossjohn, Jamie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2012
Aiheet:
Immunology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493954/
https://ncbi.nlm.nih.gov/pubmed/22995911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.412320
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