A molecular basis for the exquisite CD1d-restricted Antigen-specificity and functional responses of Natural Killer T cells

Natural Killer T (NKT) cells respond to a variety of CD1d-restricted antigens (Ags), although the basis for Ag discrimination by the NKT cell receptor (TCR) is unclear. Here we describe NKT TCR fine specificity against several closely related Ags, termed altered glycolipid ligands (AGLs), which diff...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Wun, Kwok S., Cameron, Garth, Patel, Onisha, Pang, Siew Siew, Pellicci, Daniel G., Sullivan, Lucy C., Keshipeddy, Santosh, Young, Mary H., Uldrich, Adam P., Thakur, Meena S., Richardson, Stewart K., Howell, Amy R., Illarionov, Petr A., Brooks, Andrew G., Besra, Gurdyal S., McCluskey, James, Gapin, Laurent, Porcelli, Steven A., Godfrey, Dale I., Rossjohn, Jamie
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064745/
https://ncbi.nlm.nih.gov/pubmed/21376639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.02.001
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge