A molecular basis for the exquisite CD1d-restricted Antigen-specificity and functional responses of Natural Killer T cells

Natural Killer T (NKT) cells respond to a variety of CD1d-restricted antigens (Ags), although the basis for Ag discrimination by the NKT cell receptor (TCR) is unclear. Here we describe NKT TCR fine specificity against several closely related Ags, termed altered glycolipid ligands (AGLs), which diff...

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Detaylı Bibliyografya
Asıl Yazarlar: Wun, Kwok S., Cameron, Garth, Patel, Onisha, Pang, Siew Siew, Pellicci, Daniel G., Sullivan, Lucy C., Keshipeddy, Santosh, Young, Mary H., Uldrich, Adam P., Thakur, Meena S., Richardson, Stewart K., Howell, Amy R., Illarionov, Petr A., Brooks, Andrew G., Besra, Gurdyal S., McCluskey, James, Gapin, Laurent, Porcelli, Steven A., Godfrey, Dale I., Rossjohn, Jamie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064745/
https://ncbi.nlm.nih.gov/pubmed/21376639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.02.001
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