A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition

Little is known regarding the basis for selection of the semi-invariant αβ T cell receptor (TCR) expressed by natural killer T (NKT) cells or how this mediates recognition of CD1d–glycolipid complexes. We have determined the structures of two human NKT TCRs that differ in their CDR3β composition and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kjer-Nielsen, Lars, Borg, Natalie A., Pellicci, Daniel G., Beddoe, Travis, Kostenko, Lyudmila, Clements, Craig S., Williamson, Nicholas A., Smyth, Mark J., Besra, Gurdyal S., Reid, Hugh H., Bharadwaj, Mandvi, Godfrey, Dale I., Rossjohn, Jamie, McCluskey, James
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2006
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118261/
https://ncbi.nlm.nih.gov/pubmed/16505140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051777
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