A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition

Little is known regarding the basis for selection of the semi-invariant αβ T cell receptor (TCR) expressed by natural killer T (NKT) cells or how this mediates recognition of CD1d–glycolipid complexes. We have determined the structures of two human NKT TCRs that differ in their CDR3β composition and...

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Main Authors: Kjer-Nielsen, Lars, Borg, Natalie A., Pellicci, Daniel G., Beddoe, Travis, Kostenko, Lyudmila, Clements, Craig S., Williamson, Nicholas A., Smyth, Mark J., Besra, Gurdyal S., Reid, Hugh H., Bharadwaj, Mandvi, Godfrey, Dale I., Rossjohn, Jamie, McCluskey, James
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2006
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118261/
https://ncbi.nlm.nih.gov/pubmed/16505140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051777
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