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A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition

Little is known regarding the basis for selection of the semi-invariant αβ T cell receptor (TCR) expressed by natural killer T (NKT) cells or how this mediates recognition of CD1d–glycolipid complexes. We have determined the structures of two human NKT TCRs that differ in their CDR3β composition and...

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Autors principals: Kjer-Nielsen, Lars, Borg, Natalie A., Pellicci, Daniel G., Beddoe, Travis, Kostenko, Lyudmila, Clements, Craig S., Williamson, Nicholas A., Smyth, Mark J., Besra, Gurdyal S., Reid, Hugh H., Bharadwaj, Mandvi, Godfrey, Dale I., Rossjohn, Jamie, McCluskey, James
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118261/
https://ncbi.nlm.nih.gov/pubmed/16505140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051777
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