A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR

Although it has been established how CD1 binds a variety of lipid antigens (Ag), data are only now emerging that show how αβ T cell receptors (TCRs) interact with CD1-Ag. Using the structure of the human semiinvariant NKT TCR–CD1d–α-galactosylceramide (α-GalCer) complex as a guide, we undertook an a...

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Main Authors: Wun, Kwok S., Borg, Natalie A., Kjer-Nielsen, Lars, Beddoe, Travis, Koh, Ruide, Richardson, Stewart K., Thakur, Meena, Howell, Amy R., Scott-Browne, James P., Gapin, Laurent, Godfrey, Dale I., McCluskey, James, Rossjohn, Jamie
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2008
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292230/
https://ncbi.nlm.nih.gov/pubmed/18378792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20072141
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