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Enhanced TCR footprint by a novel glycolipid increases NKT dependent tumor protection
NKT cells, a unique type of regulatory T cells, respond to structurally diverse glycolipids presented by CD1d. While it was previously thought that recognition of glycolipids such as α-GalCer by NKTCR obeys a key-lock principle, it is now clear this interaction is much more flexible. Here, we report...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3817951/ https://ncbi.nlm.nih.gov/pubmed/23960235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203134 |
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