Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis

Invariant natural killer T (iNKT) cells are known to have marked immunomodulatory capacity due to their ability to produce copious amounts of effector cytokines. Here, we report the structure and function of a novel class of aromatic α-galactosylceramide structurally related glycolipids with marked...

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Main Authors: Aspeslagh, Sandrine, Li, Yali, Yu, Esther Dawen, Pauwels, Nora, Trappeniers, Matthias, Girardi, Enrico, Decruy, Tine, Van Beneden, Katrien, Venken, Koen, Drennan, Michael, Leybaert, Luc, Wang, Jing, Franck, Richard W, Van Calenbergh, Serge, Zajonc, Dirk M, Elewaut, Dirk
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117654/
https://ncbi.nlm.nih.gov/pubmed/21552205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.145
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