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Enhanced TCR footprint by a novel glycolipid increases NKT dependent tumor protection

NKT cells, a unique type of regulatory T cells, respond to structurally diverse glycolipids presented by CD1d. While it was previously thought that recognition of glycolipids such as α-GalCer by NKTCR obeys a key-lock principle, it is now clear this interaction is much more flexible. Here, we report...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Aspeslagh, Sandrine, Nemčovič, Marek, Pauwels, Nora, Venken, Koen, Wang, Jing, Calenbergh, Serge Van, Zajonc, Dirk M., Elewaut, Dirk
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3817951/
https://ncbi.nlm.nih.gov/pubmed/23960235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203134
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