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Azithromycin attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4
Accumulation of profibrotic myofibroblasts is involved in the process of fibrosis development during idiopathic pulmonary fibrosis (IPF) pathogenesis. TGFB (transforming growth factor β) is one of the major profibrotic cytokines for myofibroblast differentiation and NOX4 (NADPH oxidase 4) has an ess...
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出版年: | Autophagy |
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主要な著者: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Taylor & Francis
2017
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584851/ https://ncbi.nlm.nih.gov/pubmed/28613983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1328348 |
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