Azithromycin attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4

Accumulation of profibrotic myofibroblasts is involved in the process of fibrosis development during idiopathic pulmonary fibrosis (IPF) pathogenesis. TGFB (transforming growth factor β) is one of the major profibrotic cytokines for myofibroblast differentiation and NOX4 (NADPH oxidase 4) has an ess...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Tsubouchi, Kazuya, Araya, Jun, Minagawa, Shunsuke, Hara, Hiromichi, Ichikawa, Akihiro, Saito, Nayuta, Kadota, Tsukasa, Sato, Nahoko, Yoshida, Masahiro, Kurita, Yusuke, Kobayashi, Kenji, Ito, Saburo, Fujita, Yu, Utsumi, Hirofumi, Yanagisawa, Haruhiko, Hashimoto, Mitsuo, Wakui, Hiroshi, Yoshii, Yutaka, Ishikawa, Takeo, Numata, Takanori, Kaneko, Yumi, Asano, Hisatoshi, Yamashita, Makoto, Odaka, Makoto, Morikawa, Toshiaki, Nakayama, Katsutoshi, Nakanishi, Yoichi, Kuwano, Kazuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Translational Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584851/
https://ncbi.nlm.nih.gov/pubmed/28613983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1328348
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