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Azithromycin attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4
Accumulation of profibrotic myofibroblasts is involved in the process of fibrosis development during idiopathic pulmonary fibrosis (IPF) pathogenesis. TGFB (transforming growth factor β) is one of the major profibrotic cytokines for myofibroblast differentiation and NOX4 (NADPH oxidase 4) has an ess...
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Vydáno v: | Autophagy |
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Hlavní autoři: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Taylor & Francis
2017
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584851/ https://ncbi.nlm.nih.gov/pubmed/28613983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1328348 |
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