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PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis
Cigarette smoke (CS)-induced accumulation of mitochondrial damage has been widely implicated in chronic obstructive pulmonary disease (COPD) pathogenesis. Mitophagy plays a crucial role in eliminating damaged mitochondria, and is governed by the PINK1 (PTEN induced putative protein kinase 1)-PRKN (p...
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| Publicado no: | Autophagy |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6351145/ https://ncbi.nlm.nih.gov/pubmed/30290714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1532259 |
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