Anti-tumor activity of selective inhibitor of nuclear export (SINE) compounds, is enhanced in non-Hodgkin lymphoma through combination with mTOR inhibitor and dexamethasone

In previous studies we demonstrated that targeting the nuclear exporter protein exportin-1 (CRM1/XPO1) by a selective inhibitor of nuclear export (SINE) compound is a viable therapeutic strategy against Non-Hodgkin Lymphoma (NHL). Our studies along with pre-clinical work from others led to the evalu...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Muqbil, Irfana, Aboukameel, Amro, Elloul, Sivan, Carlson, Robert, Senapedis, William, Baloglu, Erkan, Kauffman, Michael, Shacham, Sharon, Bhutani, Divaya, Zonder, Jeffrey, Azmi, Asfar S., Mohammad, Ramzi M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584550/
https://ncbi.nlm.nih.gov/pubmed/27693556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.09.016
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