A p53-dependent response limits the viability of mammalian haploid cells

The recent development of haploid cell lines has facilitated forward genetic screenings in mammalian cells. These lines include near-haploid human cell lines isolated from a patient with chronic myelogenous leukemia (KBM7 and HAP1), as well as haploid embryonic stem cells derived from several organi...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Olbrich, Teresa, Mayor-Ruiz, Cristina, Vega-Sendino, Maria, Gomez, Carmen, Ortega, Sagrario, Ruiz, Sergio, Fernandez-Capetillo, Oscar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2017
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584429/
https://ncbi.nlm.nih.gov/pubmed/28808015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705133114
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