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Coordinating ERK signaling via the molecular scaffold Kinase Suppressor of Ras
Many cancers, including those of the colon, lung, and pancreas, depend upon the signaling pathways induced by mutated and constitutively active Ras. The molecular scaffolds Kinase Suppressor of Ras 1 and 2 (KSR1 and KSR2) play potent roles in promoting Ras-mediated signaling through the Raf/MEK/ERK...
Guardat en:
| Publicat a: | F1000Res |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
F1000Research
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5583734/ https://ncbi.nlm.nih.gov/pubmed/29026529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.11895.1 |
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