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Coordinating ERK signaling via the molecular scaffold Kinase Suppressor of Ras

Many cancers, including those of the colon, lung, and pancreas, depend upon the signaling pathways induced by mutated and constitutively active Ras. The molecular scaffolds Kinase Suppressor of Ras 1 and 2 (KSR1 and KSR2) play potent roles in promoting Ras-mediated signaling through the Raf/MEK/ERK...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:F1000Res
Päätekijät: Frodyma, Danielle, Neilsen, Beth, Costanzo-Garvey, Diane, Fisher, Kurt, Lewis, Robert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: F1000Research 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583734/
https://ncbi.nlm.nih.gov/pubmed/29026529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.11895.1
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