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Kinase Suppressor of Ras 2 (KSR2) expression in the brain regulates energy balance and glucose homeostasis
OBJECTIVE: Kinase Suppressor of Ras 2 (KSR2) is a molecular scaffold coordinating Raf/MEK/ERK signaling that is expressed at high levels in the brain. KSR2 disruption in humans and mice causes obesity and insulin resistance. Understanding the anatomical location and mechanism of KSR2 function should...
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| Publicado no: | Mol Metab |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5279912/ https://ncbi.nlm.nih.gov/pubmed/28180061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.12.004 |
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