Kinase Suppressor of Ras 2 (KSR2) expression in the brain regulates energy balance and glucose homeostasis

OBJECTIVE: Kinase Suppressor of Ras 2 (KSR2) is a molecular scaffold coordinating Raf/MEK/ERK signaling that is expressed at high levels in the brain. KSR2 disruption in humans and mice causes obesity and insulin resistance. Understanding the anatomical location and mechanism of KSR2 function should...

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Dades bibliogràfiques
Publicat a:Mol Metab
Autors principals: Guo, Lili, Costanzo-Garvey, Diane L., Smith, Deandra R., Neilsen, Beth K., MacDonald, Richard G., Lewis, Robert E.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5279912/
https://ncbi.nlm.nih.gov/pubmed/28180061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.12.004
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