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Small molecule T63 suppresses osteoporosis by modulating osteoblast differentiation via BMP and WNT signaling pathways

Osteoporosis results from the imbalance between bone resorption and bone formation, and restoring the normal balance of bone remodeling is highly desirable for identification of better treatment. In this study, using a cell-based high-throughput screening model representing Runt-related transcriptio...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Zhao, Xiao-li, Chen, Jin-jing, Zhang, Guo-ning, Wang, Yu-cheng, Si, Shu-yi, Chen, Lin-Feng, Wang, Zhen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583318/
https://ncbi.nlm.nih.gov/pubmed/28871136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10929-3
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