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Small molecule T63 suppresses osteoporosis by modulating osteoblast differentiation via BMP and WNT signaling pathways

Osteoporosis results from the imbalance between bone resorption and bone formation, and restoring the normal balance of bone remodeling is highly desirable for identification of better treatment. In this study, using a cell-based high-throughput screening model representing Runt-related transcriptio...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Zhao, Xiao-li, Chen, Jin-jing, Zhang, Guo-ning, Wang, Yu-cheng, Si, Shu-yi, Chen, Lin-Feng, Wang, Zhen
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583318/
https://ncbi.nlm.nih.gov/pubmed/28871136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10929-3
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