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Small molecule modulators of Wnt/β-catenin signaling

The Wnt signal transduction pathway is dysregulated in many highly prevalent diseases, including cancer. Unfortunately, drug discovery efforts have been hampered by the paucity of targets and drug-like lead molecules amenable to drug discovery. Recently, we reported the FDA-approved anthelmintic dru...

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Autori principali: Mook, Robert A., Chen, Minyong, Lu, Jiuyi, Barak, Larry S., Lyerly, H. Kim, Chen, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660039/
https://ncbi.nlm.nih.gov/pubmed/23453073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.01.101
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