Decreased phosphatase PTEN amplifies PI3K signaling and enhances proinflammatory cytokine release in COPD

The phosphatidylinositol 3-kinase (PI3K) pathway is activated in chronic obstructive pulmonary disease (COPD), but the regulatory mechanisms for this pathway are yet to be elucidated. The aim of this study was to determine the expression and role of phosphatase and tensin homolog deleted from chromo...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Lung Cell Mol Physiol
Asıl Yazarlar: Yanagisawa, Satoru, Baker, Jonathan R., Vuppusetty, Chaitanya, Fenwick, Peter, Donnelly, Louise E., Ito, Kazuhiro, Barnes, Peter J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582930/
https://ncbi.nlm.nih.gov/pubmed/28522564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00382.2016
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